Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.7
USERS' SCORE
Good
Based on 13 Reviews
8.4
Supplement Facts
Serving Size: 2 Enteric Coated Softgels
Amount Per Serving
%DV
Calories
25
Total Fat
2.5 g
4%†
Cholesterol
<5 mg
2%†
Pure+™ Wild Fish Oil ConcentrateYielding: EPA (eicosapentaenoic acid)DHA (docosahexaenoic acid)
2,000 mg700 mg500 mg
******
Polyphen-Oil™ Olive extract (fruit and leaf)[providing 19.5 mg polyphenols, 5.2 mg hydroxytyrosol/tyrosol, 4.4 mg verbascoside/oleuropein]
300 mg
**
Sesame seed lignan extract
10 mg
**
Top Medical Research Studies
9
We investigated the link between plasma omega-3 levels and the risk of heart failure (HF) in a large UK cohort study. Our analysis revealed that higher omega-3 levels were associated with a 21% lower chance of developing HF over nearly 14 years.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
Read More
9
Omega-3 reduces cardiovascular risk
We observed the effects of icosapent ethyl on heart health in a significant clinical trial involving statin-treated patients at high risk for cardiovascular events. This post hoc analysis revealed that icosapent ethyl reduced major cardiovascular issues, regardless of whether patients had low-density lipoprotein cholesterol (LDL-C) levels below or above 55 mg/dL.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Read More
8
We explored the impact of eicosapentaenoic acid (EPA) on heart health by studying mice on a high-fat diet. Those supplemented with EPA showed a significant reduction in atrial fibrillation compared to those without. While 100% of the high-fat diet mice developed atrial fibrillation, only 50% of those receiving EPA did, and their episodes were shorter.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Read More
Most Useful Reviews
9
Improves heart function
5 people found this helpful
Fish oil is highly beneficial and should be consumed daily. It improves blood pressure, vision, brain function, skin condition, and strengthens immunity. Most importantly, it boosts cardiovascular health. I recommend taking three capsules a day; there’s no unpleasant smell.
Read More
9
Promotes health benefits
Amazing! It promotes cardiovascular health and cognitive wellbeing, effectively maintaining triglyceride, HDL, and LDL cholesterol levels. It includes heart-healthy Mediterranean sesame and olive extracts and features IFOS™ certified anchovies that are sustainably sourced from the South Pacific coast of Chile.
Read More
7.5
Supports heart function
This fish oil supplement, with its high-quality ingredients, is designed to support cardiovascular health, brain function, and overall wellness. I’m encouraged by its Mediterranean-inspired formulation, which combines omega-3 fatty acids with beneficial olive polyphenols and sesame lignans.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.7
- All Researches
9
Omega-3 reduces cardiovascular risk
We observed the effects of icosapent ethyl on heart health in a significant clinical trial involving statin-treated patients at high risk for cardiovascular events. This post hoc analysis revealed that icosapent ethyl reduced major cardiovascular issues, regardless of whether patients had low-density lipoprotein cholesterol (LDL-C) levels below or above 55 mg/dL.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Notably, those with optimal LDL-C control still benefited from the treatment, showing that this fish oil derivative can be effective in managing heart risks for many patients.
Read More
9
We assessed how omega-3 fatty acids (PUFAs) can support heart failure management through a thorough network meta-analysis of 14 studies with nearly 9,100 participants.
Our findings revealed that high doses (2,000-4,000 mg/day) taken for at least one year significantly improved heart function, particularly the left ventricular ejection fraction and peak oxygen consumption.
However, lower doses and shorter durations were not effective, and we found no major differences in safety measures like dropout rates or overall mortality between those taking omega-3 and those who were not.
Our findings revealed that high doses (2,000-4,000 mg/day) taken for at least one year significantly improved heart function, particularly the left ventricular ejection fraction and peak oxygen consumption.
However, lower doses and shorter durations were not effective, and we found no major differences in safety measures like dropout rates or overall mortality between those taking omega-3 and those who were not.
Read More
9
We investigated the link between plasma omega-3 levels and the risk of heart failure (HF) in a large UK cohort study. Our analysis revealed that higher omega-3 levels were associated with a 21% lower chance of developing HF over nearly 14 years.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
Read More
8
This study examined how different fatty acids affect heart health, particularly focusing on long-chain acylcarnitines. We found that saturated and monounsaturated acylcarnitines, especially one type called trans-elaidoylcarnitine, can significantly harm heart function and cell viability.
On the other hand, omega-3 derived acylcarnitines like eicosapentaenoylcarnitine and docosahexaenoylcarnitine showed minimal negative effects. In fact, they did not impair heart function or cell viability, suggesting that omega-3 fish oil might be a safer option for people with heart issues compared to other fatty acid sources.
On the other hand, omega-3 derived acylcarnitines like eicosapentaenoylcarnitine and docosahexaenoylcarnitine showed minimal negative effects. In fact, they did not impair heart function or cell viability, suggesting that omega-3 fish oil might be a safer option for people with heart issues compared to other fatty acid sources.
Read More
8
We explored the impact of eicosapentaenoic acid (EPA) on heart health by studying mice on a high-fat diet. Those supplemented with EPA showed a significant reduction in atrial fibrillation compared to those without. While 100% of the high-fat diet mice developed atrial fibrillation, only 50% of those receiving EPA did, and their episodes were shorter.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Read More
User Reviews
USERS' SCORE
Good
Based on 13 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Improves heart function
5 people found this helpful
Fish oil is highly beneficial and should be consumed daily. It improves blood pressure, vision, brain function, skin condition, and strengthens immunity. Most importantly, it boosts cardiovascular health. I recommend taking three capsules a day; there’s no unpleasant smell.
Read More
9
Promotes health benefits
Amazing! It promotes cardiovascular health and cognitive wellbeing, effectively maintaining triglyceride, HDL, and LDL cholesterol levels. It includes heart-healthy Mediterranean sesame and olive extracts and features IFOS™ certified anchovies that are sustainably sourced from the South Pacific coast of Chile.
Read More
7.5
Supports heart function
This fish oil supplement, with its high-quality ingredients, is designed to support cardiovascular health, brain function, and overall wellness. I’m encouraged by its Mediterranean-inspired formulation, which combines omega-3 fatty acids with beneficial olive polyphenols and sesame lignans.
Read More
9
Pain relief experienced
57 people found this helpful
I don’t typically write reviews, but I had to make an exception for this product. After struggling with my weight and chronic pain, I discovered that my issues might be related to arthritis. After I began taking this supplement, my pain vanished almost completely the very next day. I was astonished! My mobility has remarkably improved, and my mother has also experienced enhancement in her knee mobility. This product has truly changed our lives, and I intend to continue using it.
Read More
7.5
Supports cardiovascular health
15 people found this helpful
Excellent composition with effective omega. This omega supplement aids the cardiovascular system and strengthens the immune system. The capsules are larger and somewhat difficult to swallow for me, but there's no unpleasant aftertaste. Olive leaf extract is a beneficial addition.
Read More
Frequently Asked Questions
8
Supports heart health
1 people found this helpful
This supplement excellently supports heart health, improves cognitive function, and reduces inflammation. After using it, I noticed enhanced heart function and greater focus. I recommend it for anyone wanting to support their cardiovascular health.
7.5
Protects heart health
I find fish omega beneficial for maintaining heart health. It doesn't have a strong fishy taste, and even when burping, it’s not unpleasant. I trust this brand and have seen positive effects on my cardiovascular health and overall condition.
9
Reduces cholesterol
1 people found this helpful
Omega-3 fatty acids help to clear blood vessels of bad cholesterol and reduce cardiovascular disease risks. They also improve brain function and emotional well-being. Supplementing with omega-3 offers numerous health benefits, including reducing inflammation and enhancing overall tone.
9
Improves heart function
5 people found this helpful
Fish oil is highly beneficial and should be consumed daily. It improves blood pressure, vision, brain function, skin condition, and strengthens immunity. Most importantly, it boosts cardiovascular health. I recommend taking three capsules a day; there’s no unpleasant smell.
7.5
Encourages cardiovascular health
Super Omega-3 supplies essential EPA and DHA fatty acids, promoting cardiovascular health and brain function. Inspired by the Mediterranean diet, it includes valuable olive polyphenols and sesame lignans for comprehensive health benefits.
8
We examined the effects of dietary omega-3 polyunsaturated fatty acids (Dω-3 PUFAs) on cardiovascular diseases (CVDs) through recent clinical trials and food fortification trends.
Evidence suggests that these beneficial fatty acids can lower heart disease risk, improve blood pressure, and enhance lipid profiles.
While advancements in fortifying foods with Dω-3 PUFAs show promise, there's still a need for more research to maximize their health benefits and ensure better protection against CVDs.
Evidence suggests that these beneficial fatty acids can lower heart disease risk, improve blood pressure, and enhance lipid profiles.
While advancements in fortifying foods with Dω-3 PUFAs show promise, there's still a need for more research to maximize their health benefits and ensure better protection against CVDs.
8
Diet and fish oil improve heart health
We explored how dietary changes, particularly the MoKaRi diet, can impact cardiovascular health. In a 20-week study with 65 participants, individualized meal plans were combined with fish oil supplements to assess their effects on various cardiometabolic risk factors.
The results showcased significant reductions in cholesterol levels, body weight, and other critical indicators. Notably, those who incorporated fish oil saw even greater improvements in weight loss and blood sugar levels. This research suggests that pairing a healthy diet with fish oil can enhance cardiovascular outcomes.
The results showcased significant reductions in cholesterol levels, body weight, and other critical indicators. Notably, those who incorporated fish oil saw even greater improvements in weight loss and blood sugar levels. This research suggests that pairing a healthy diet with fish oil can enhance cardiovascular outcomes.
8
We explored the impact of eicosapentaenoic acid (EPA) on heart health by studying mice on a high-fat diet. Those supplemented with EPA showed a significant reduction in atrial fibrillation compared to those without. While 100% of the high-fat diet mice developed atrial fibrillation, only 50% of those receiving EPA did, and their episodes were shorter.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
Our findings suggest that including EPA in the diet can help improve heart function and reduce irregular heart rhythms linked to high-fat diets.
9
We investigated the link between plasma omega-3 levels and the risk of heart failure (HF) in a large UK cohort study. Our analysis revealed that higher omega-3 levels were associated with a 21% lower chance of developing HF over nearly 14 years.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
For individuals already diagnosed with HF, elevated omega-3 levels corresponded to about a 50% reduction in the risk of overall and cardiovascular mortality. These results suggest that boosting omega-3 intake through diet or supplements may help prevent HF and increase longevity for those already facing heart challenges.
8
We investigated the role of omega-3 polyunsaturated fatty acids (PUFAs) in preventing cardiovascular disease through a meta-analysis of randomized clinical trials.
Our findings indicated that prescription medications containing PUFAs may reduce the risk of cardiovascular events, including heart attacks and cardiac death.
However, while these results contribute valuable insights, the overall cardioprotective effects remain a topic of debate.
This research helps clarify how PUFA medications fit into heart health strategies.
Our findings indicated that prescription medications containing PUFAs may reduce the risk of cardiovascular events, including heart attacks and cardiac death.
However, while these results contribute valuable insights, the overall cardioprotective effects remain a topic of debate.
This research helps clarify how PUFA medications fit into heart health strategies.
9
We assessed how omega-3 fatty acids (PUFAs) can support heart failure management through a thorough network meta-analysis of 14 studies with nearly 9,100 participants.
Our findings revealed that high doses (2,000-4,000 mg/day) taken for at least one year significantly improved heart function, particularly the left ventricular ejection fraction and peak oxygen consumption.
However, lower doses and shorter durations were not effective, and we found no major differences in safety measures like dropout rates or overall mortality between those taking omega-3 and those who were not.
Our findings revealed that high doses (2,000-4,000 mg/day) taken for at least one year significantly improved heart function, particularly the left ventricular ejection fraction and peak oxygen consumption.
However, lower doses and shorter durations were not effective, and we found no major differences in safety measures like dropout rates or overall mortality between those taking omega-3 and those who were not.
References
- Liepinsh E, Gukalova B, Krims-Davis K, Kuka J, Leduskrasta A, et al. EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines. Biofactors. 2025;51:e70014. 10.1002/biof.70014
- Medoro A, Graziano F, Cardinale G, Voccola S, Zotti T, et al. The influence of FADS1 and ELOVL2 genetic polymorphisms on polyunsaturated fatty acid composition in response to fish oil supplementation. Lipids Health Dis. 2025;24:102. 10.1186/s12944-025-02513-w
- Horii K, Ono K, Sumi T, Higashihara M, Zaima N, et al. Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice. J Physiol Sci. 2025;75:100014. 10.1016/j.jphyss.2025.100014
- Dawczynski C, Drobner T, Weidauer T, Schlattmann P, Kiehntopf M, et al. Reduction of cardiovascular risk factors by the diet - Evaluation of the MoKaRi concept by a parallel-designed randomized study. Lipids Health Dis. 2025;24:88. 10.1186/s12944-025-02500-1
- Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, et al. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025;14:e038656. 10.1161/JAHA.124.038656
- Mao Q, Tian X, Wang X, Xu H, Zhang Y, et al. Global burden of cardiovascular diseases attributable to diet low in seafood omega-3 fatty acids from 1990~2021 and forecasting the future trends: A population-based study. PLoS One. 2025;20:e0316767. 10.1371/journal.pone.0316767
- Tseng PT, Zeng BY, Hsu CW, Liang CS, Stubbs B, et al. The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis. Adv Nutr. 2025;16:100366. 10.1016/j.advnut.2025.100366
- Hemmati R, Bahrami Zanjanbar D, Shishesaz MI, Soleimani A, Yari T. The impact of Omega-3 supplementation on arrhythmia reduction in acute coronary syndrome patients: a randomized clinical trial. J Complement Integr Med. 2025;22:173. 10.1515/jcim-2024-0427
- Wang Y, Wu G, Wang Y, Rehman A, Yu L, et al. Recent developments, challenges, and prospects of dietary omega-3 PUFA-fortified foods: Focusing on their effects on cardiovascular diseases. Food Chem. 2025;470:142498. 10.1016/j.foodchem.2024.142498
- Dong S, Wang Y, Bian J, Chen H, Dong J, et al. The effect of omega-3 Polyunsaturated Fatty Acid (PUFA) prescription preparations on the prevention of clinical cardiovascular disease: a meta-analysis of RCTs. Nutr J. 2024;23:157. 10.1186/s12937-024-01051-y
- Jawad MA, O'Keefe JH, Tintle N, O'Keefe EL, Franco WG, et al. Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities. Mayo Clin Proc. 2024;99:1895. 10.1016/j.mayocp.2024.08.007
- Brosolo G, Da Porto A, Marcante S, Capilupi F, Bertin N, et al. The role for ω-3 polyunsaturated and short chain fatty acids in hypertension: An updated view on the interaction with gut microbiota. Eur J Pharmacol. 2024;985:177107. 10.1016/j.ejphar.2024.177107
- Lee YQ, Tan KH, Chong MF. Biomarkers of PUFA and cardiovascular risk factors and events in healthy Asian populations: a systematic review. Br J Nutr. 2024;132:1474. 10.1017/S0007114524002708
- Li J, Nan W, Huang X, Meng H, Wang S, et al. Eicosapentaenoic acid induces macrophage Mox polarization to prevent diabetic cardiomyopathy. EMBO Rep. 2024;25:5507. 10.1038/s44319-024-00271-x
- Li ZH, Song WQ, Qiu CS, Li HM, Tang XL, et al. Fish oil supplementation, genetic susceptibility and risk of new-onset hypertension. Prev Med. 2024;189:108152. 10.1016/j.ypmed.2024.108152
